Introduction

epiTOol is a web-based application for transplantation immunogenetics (immunology), providing easy and reliable translation of high-resolution HLA typing into epitopes.
Unlike other similar tools, epiTOol allows for upload and analysis of large datasets of patient-donor combinations without the need for manual data entry.

  • Direct data import and export
  • Overview of alleles and corresponding epitopes
  • Antibody profiling
  • Epitope-based donor-recipient matching and mismatching
  • (Mis)matching in single individual and pairwise mode

Article & file templates

Please find the corresponding article here:

Citation:

  • C. Lehmann, N. Lachmann, I. Doxiadis & H. Loeffler-Wirth: epiTOol: A browser-based HLA epitope (mis)matching application for small to large cohorts. Frontiers in Immunology 2026

Data files need to follow format instructions given in the article. Please also see the file templates below:

Register

Please fill the form below and send the generated email. No username or password is required.
epiTOol can be used once your registration is confirmed.


I understand that epiTOol is designed for research purposes only.
I agree that data files are transferred to and processed by epiTOol.
Neither data files will nor analysis results will be stored by epiTOol.